A method for the catalytic formation of electroauxiliaries and subsequent anodic oxidation has been developed. The process interfaces N-heterocyclic carbene-based organocatalysis with electro-organic synthesis to achieve direct oxidation of catalytically generated electroactive intermediates. We demonstrate the applicability of this method as a one-pot conversion of aldehydes to esters for a broad range of aldehyde and alcohol substrates. Furthermore, the anodic oxidation reactions are very clean, producing only H2 gas as a result of cathodic reduction.
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Publications by AJ Boydston from Undergraduate, Graduate, and Postdoctoral Work
Momčilović, N.; Clark, P. G.; Boydston, A. J.*; Grubbs, R. H.* “One-Pot Synthesis of Polyrotaxanes via Acyclic Diene Metathesis Polymerization of Supramolecular Monomers” J. Am. Chem. Soc. 2011, 133, 19087-19089. (*Co-corresponding authors) Xia, Y.; Boydston, A. J.; Grubbs, …